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KMID : 0357820160400040099
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Korean Journal of Legal Medicine
2016 Volume.40 No. 4 p.99 ~ p.103
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Usefulness of Dipstick Test for Vitreous Glucose in Autopsy Practice
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Lee Kyung-Hong
Koo Hyung-Nam
Kim Tae-Gong
Park Jeong-Yeol
Baek Kang-Hyun
Choi Seung-Gyu
Choi Cheol-Ho
Aum Na-Hyun
Lee Nak-Won
Choi Byung-Ha
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Abstract
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The concentration of glucose in the vitreous humor serves as an important diagnostic marker for diabetic mellitus in post-mortem examinations, as the vitreous humor can be easily collected and the glucose test using vitreous humor is not significantly affected by cell autolysis and hemolysis. For a quick and effective glucose test, we suggest a dipstick test of the vitreous humor during autopsy. The results were evaluated and compared with other methods for significance testing. In this study, vitreous humor was analyzed from 257 autopsy cases. Qualitative concordance rate of the dipstick test for glucose and the hexokinase test was 98.7%, positive prediction rate was 89.6%, and negative prediction rate was 100%. However, there was no significant correlation between the dipstick glucose test and the hexokinase test. We conclude that the dipstick glucose test is effective and useful for post-mortem glucose screening testing and for additional post- mortem diabetes testing. Recently, the importance of post-mortem glucose testing has increased with the increase in deaths from diabetes complications. The use of the dipstick glucose test in autopsy practice can improve forensic medicine in Korea.
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KEYWORD
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Vitreous humor, Glucose, Diabetic mellitus, Autopsy
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